Farmacologia Cellulare e Traslazionale

Laboratorio del Metabolismo Lipidico e Tumorale

Pubblicazioni recenti

  • D'Errico I, Salvatore L, Murzilli S, Lo Sasso G, Latorre D, Martelli N, Egorova AV, Polishuck R, Madeyski-Bengtson K, Lelliott C, Vidal-Puig AJ, Seibel P, Villani G, Moschetta A.
    Peroxisome proliferator-activated receptor-{gamma} coactivator 1-{alpha} (PGC1{alpha}) is a metabolic regulator of intestinal epithelial cell fate.
    Proc Natl Acad Sci U S A. 108(16):6603-8 (2011).
    PubMed Full text
  • Lo Sasso G, Murzilli S, Salvatore L, D'Errico I, Petruzzelli M, Conca P, Jiang ZY, Calabresi L,Parini P, Moschetta A.
    Intestinal specific LXR activation stimulates reverse cholesterol transport and protects from atherosclerosis.
    Cell Metab. 12:187-193 (2010).
    PubMed Full text
  • Lo Sasso G., Celli N., Caboni M., Murzilli S., Salvatore L., Morgano A., Vacca M., Pagliani T., Parini P., Moschetta A.
    Down-regulation of the LXR transcriptome provides the requisite cholesterol levels to proliferating hepatocytes.
    Hepatology, 51: 1334-1344 (2010).
    PubMed Full text
  • Modica S, Gofflot F, Murzilli S, D'Orazio A, Salvatore L, Pellegrini F, Nicolucci A, Tognoni G, Copetti M, Valanzano R, Veschi S, Mariani-Costantini R, Palasciano G, Schoonjans K, Auwerx J, Moschetta A.
    The Intestinal Nuclear Receptor Signature With Epithelial Localization Patterns and Expression Modulation in Tumors.
    Gastroenterology, 138(2): 636-648 (2010). (Cover capture)
    PubMed Full text Cover
  • Modica S., Morgano A., Salvatore L., Petruzzelli M., Vanier M.T., Valanzano R., Esposito D.L., Palasciano G., Duluc I., Freund J.N., Mariani-Costantini R., Moschetta A.
    Expression and localisation of insulin receptor substrate 2 in normal intestine and colorectal tumours. Regulation by intestine-specific transcription factor CDX2.
    Gut, 58: 1250-1259 (2009). (Cover capture)
    PubMed Full text Cover

 

Pubblicazioni significative

  • D'Errico I, Salvatore L, Murzilli S, Lo Sasso G, Latorre D, Martelli N, Egorova AV, Polishuck R, Madeyski-Bengtson K, Lelliott C, Vidal-Puig AJ, Seibel P, Villani G, Moschetta A.
    Peroxisome proliferator-activated receptor-{gamma} coactivator 1-{alpha} (PGC1{alpha}) is a metabolic regulator of intestinal epithelial cell fate.
    Proc Natl Acad Sci U S A. 108(16):6603-8 (2011).
    PubMed Full text
  • Lo Sasso G, Murzilli S, Salvatore L, D'Errico I, Petruzzelli M, Conca P, Jiang ZY, Calabresi L,Parini P, Moschetta A.
    Intestinal specific LXR activation stimulates reverse cholesterol transport and protects from atherosclerosis.
    Cell Metab. 12:187-193 (2010).
    PubMed Full text
  • Moschetta A., Bookout A.L., Mangelsdorf D.J.
    Prevention of cholesterol gallstone disease by FXR agonists in a mouse model.
    Nat. Med., 10: 1352-1358 (2004). (Cover capture)
    PubMed Full text Cover
  • Moschetta A, vanBerge-Henegouwen G.P., Portincasa P., Palasciano G., Groen A.K., van Erpecum K.J.
    Sphingomyelin exhibits greatly enhanced protection compared with egg yolk phosphatidylcholine against detergent bile salts.
    J. Lipid Res., 41: 916-924 (2000).
    PubMed Full text
  • Modica S., Murzilli S., Salvatore L., Schmidt D.R., Moschetta A.
    Nuclear bile acid receptor FXR protects against intestinal tumorigenesis.
    Cancer Res., 68: 9589-9594 (2008). (Cover capture)
    PubMed Full text Cover

 

ultimo aggiornamento: 04-05-2011