Pubblicazioni recenti

• Chiacchiera F., Simone C.
  The AMPK-FoxO3A axis as a target for cancer treatment.
  Cell Cycle, 9(6) In Press (2010)
  Abstract
• Matrone A., Grossi V., Chiacchiera F., Fina E., Cappellari M., Caringella A.M., Di Naro E., Loverro G., Simone C.
  p38[alpha] is Required for Ovarian Cancer Cell Metabolism and Survival.
  Int. J. Gynecol. Cancer, 20: 203-211 (2010)
  Abstract Full text
• Chiacchiera F., Simone C.
  Inhibition of p38alpha unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism.
  Autophagy, 5(7):1030-3. Epub Oct 12 (2009).
  PubMed Full text
• Chiacchiera F., Matrone A., Ferrari E., Ingravallo G., Lo Sasso G., Murzilli S., Petruzzelli M., Salvatore L., Moschetta A., Simone C.
  p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription.
  Cell Death Differ, Epub 3 April (2009).
  PubMed Full text
• Chiacchiera F., Simone C.
  Signal-dependent control of autophagy-related gene expression.
  Methods Enzymol., 453: 305-324 (2009).
  PubMed Full text

Pubblicazioni significative

• Chiacchiera F., Matrone A., Ferrari E., Ingravallo G., Lo Sasso G., Murzilli S., Petruzzelli M., Salvatore L., Moschetta A., Simone C.
  p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription.
  Cell Death Differ, Epub 3 April (2009).
  PubMed Full text
• Comes F., Matrone A., Lastella P., Nico B., Susca F.C., Bagnulo R., Ingravallo G., Modica S., Lo Sasso G., Moschetta A., Guanti G., Simone C.
  A novel cell type-specific role of p38alpha in the control of autophagy and cell death in colorectal cancer cells.
  Cell Death Differ., 14: 693-702 (2007).
  PubMed Full text
• Serra C., Palacios D., Mozzetta C., Forcales S., Jones D., Du K., Jhala U.S, Simone C., Puri P.L.
  Functional interdependence at the chromatin level between the p38 and IGF1/PI3K/AKT pathways.
  Mol. Cell, 28: 200-213 (2007).
  PubMed Full text
• Simone C., Forcales S.V., Hill D.A., Imbalzano A.N., Latella L., Puri P.L.
  p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci.
  Nat. Genet., 36: 738-743 (2004).
  PubMed Full text
• Iezzi S., Di Padova M., Serra C., Caretti G., Simone C., Maklan E., Minetti G., Zhao P., Hoffman E.P., Puri P.L., Sartorelli V.
  Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin.
  Dev. Cell, 6: 673-684 (2004).
  PubMed Full text

ultimo aggiornamento: 11-01-2010